Sri Rahayu Lestari, Muhammad Sasmito Djati, Ahmad Rudijanto, Fatchiyah Fatchiyah


Rambutan is a tropical fruit that grow well in Indonesia and the peel is considered as waste. Many researchers’ showed that rambutan peel contains polyphenol that could be expected to avoid obesity.  The objective of this study was to explore the increasing production of local rambutan and to identify the promising phytochemical compounds on its peel as phytopharmaca candidate against obesity. Survey was conducted on the production of rambutan, potential plantation area, and marketing. Sample of rambutan peel collected from the sub-district Kanigoro, Blitar. Phytochemical compounds were analyzed using TLC, HPLC and FT-IR. Bioassay analysis used obesity rat models. The survey result showed a mean of rambutan production increased 2,6% in 2007-2012. Average production of rambutan 70-120 kg/tree. Vegetative multiplication usually done to maintenance of rambutan quality. The main compound of  Rambutan peel  extract (RPE) is flavonoids, tannins, ellagic acid and the major functional group of CH3, aliphatic CH3, and C=O. These compounds have a potential activity against obesity.  RPE 30 mg/kgBW dose was significantly inhibit the weight gain of obese rats and reducing the adipocyte size (p<0.05).

Key words: potency, production, local rambutan, blitar, obesity

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Atkinson, C.J., P.A.A. Dodds, Y.Y. Ford, J. Le Miere, J.M. Taylor, P.S. Blake dan N. Paul., 2006. Effects of Cultivar , Fruit Number and Reflected Photosynthetically Active Radiation on Fragaria • ananassa Productivity and Fruit Ellagic Acid and Ascorbic Acid Concentrations. Annals of Botany, 97, pp.429–441.

Bajerska, J. et al., 2011. Green tea aqueous extract reduces visceral fat and decreases protein availability in rats fed with a high-fat diet. Nutrition Research, 31, pp.157–164.

Campos KE, VolpatoGT, CalderonIMP, Rudge MVC& Damasceno DC., 2008. Effect of obesity on rat reproduction and on the development of their adult offspring. Brazilian Journal of medical and Biological Research, 41, pp.122–125.

Firdausi, L. Indra, M.R., F. Fatchiyah., 2012. Binding Inhibition Between Igf-1r and Igf-1 by Catechin of Black Tea. , 2(3), pp.132–135.

Ho C, Lai Y, Wang D, Chen Y, Lee J, Tang N, Chung J., 2005. Effects of Ellagic Acid by Oral Administration on Distribution and Metabolism of 2-Aminofluorene in Sprague-Dawley Rats. , 156, pp.143–156.

ItoY, IchikawaT., Morohoshi Y, Nakamura T, Saegusa Y, Ishihara K., 2008. Effect of tea catechins on body fat accumaltion in rat fed a normal diet. Biomedical Research, 29, pp.27–32.

Ling LT, Radhakrishnan AK, Subramaniam T, Cheng HM, PalanisamyUD., 2010. Assessment of antioxidant capacity and cytotoxicity of selected Malaysian plants. Molecules (Basel, Switzerland), 15(4), pp.2139–51.

Min SY, Yang H, Seo SG, Shin SH, Chung M, Kim J, Lee SJ.., 2012. Cocoa polyphenols suppress adipogenesis in vitro and obesity in vivo by targeting insulin receptor. International Journal of Obesity, 2(October 2011), pp.1–9.

Okonogi, S., Duangrat, C. & Anuchpreeda, S. Tachakittirungrod, S. Chowwanapoonpohn, S., 2007. Comparison of antioxidant capacities and cytotoxicities of certain fruit peels. Food Chemistry, 103(3), pp.839–846.

Samsuraida, A., Mahanani, M.C. & Choong, C.., 2009. PHYLOGENETIC STUDY OF Nephelium SPECIES BASED ON THE. In August 2009. Genting, Haighland, pp. 4–6.

Statistic Indonesia and Diretorate Generale of Horticulture, 2012. Food Production in Indonesia, Jakarta.

Thitilertdecha N, Teerawutgulrag A, Kilburn JD, Rakariyatham N., 2010. Identification of Major Phenolic Compounds from Nephelium lappaceum L. and Their Antioxidant Activities. Molecules, 15, pp.1453–1465.

Tindall, H.D., U.G., M. & A.J., H., 1994. Rambutan Cultivation. In FAO Plant Production and Protection Devision. Rome, Italy: Cransfield Institute of Technology.

Wulandari, N. & Lestari, S.., 2012. The Potency of Rambutan (Nephelium Lappaceum) Peel Ethanolic Extract as an Antioxidant Natural Source Based on Viability Endotel Cell. In International Conference of Life Sciencies 2012 (ICLS 2012), Brawijaya University. Malang, Indonesia: Brawijaya University, pp. 115–119.

ZhaoXY, Liang WJ, Fan HJ, Ma QY, Tian WX, Dai HF, Jiang HZ, Li N, Ma FX.., 2011. Fatty acid synthetase unhibitors from the hulls of Nephelium lappaceum L. Carbohidrate Research, (346), pp.1302–1306.

Zheng G, Sayama K., Okubo T, Juneja LR,Oguni I., 2004. Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine in mice. In Vivo, 18, pp.55–82.


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